Impact of Optic Nerve Tortuosity, Globe Proptosis, and Size on Retinal Ganglion Cell Thickness Across General, Glaucoma, and Myopic Populations
Straighter optic nerves and decreased ILPP distance could cause RNFL thinning, possibly due to greater traction forces. ILPP distance emerged as a potential biomarker of axonal health. These findings underscore the importance of orbit structures in RGC axonal health and warrant further research into orbit biomechanics.
Authors
- Martin L. Buist (ORCID: https://orcid.org/0000-0003-3095-3358)
- Michaël J. A. Girard (ORCID: https://orcid.org/0000-0003-4408-5918)
- Charis Y. N. Chiang
- Stuart K. Gardiner (ORCID: https://orcid.org/0000-0002-9139-4943)
- Xiaofei Wang (ORCID: https://orcid.org/0000-0003-3832-5217)
Institutions
- Georgia Institute of Technology (US)
- Emory University (US)
- Legacy Health (US)
- National University of Singapore (SG)
- Singapore National Eye Center (SG)
- Singapore Eye Research Institute (SG)
- Duke-NUS Medical School (SG)
- Beihang University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1167/iovs.66.6.4
- Citations
- 2
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- Glaucoma Research Foundation
- Research to Prevent Blindness
- BrightFocus Foundation
- Emory University
- National Institutes of Health
- National Medical Research Council
- Emory Eye Center