Prevalence of Epilepsy in Frontotemporal Dementia and Timing of Dementia Diagnosis
This case-control study found a higher prevalence of epilepsy and increased ASM use among patients with FTD compared with HCs and patients with AD , suggesting an association between epileptic abnormalities and the pathophysiology of FTD. Further studies are warranted to investigate a potential overlap in the pathophysiologic mechanisms of epilepsy and FTD.
Authors
- Annakaisa Haapasalo (ORCID: https://orcid.org/0000-0003-0959-2957)
- Helmi Soppela (ORCID: https://orcid.org/0009-0006-5047-7415)
- Eino Solje (ORCID: https://orcid.org/0000-0001-9940-9524)
- Päivi Hartikainen (ORCID: https://orcid.org/0000-0003-4081-9216)
- Laura Leppänen (ORCID: https://orcid.org/0009-0009-1953-9368)
- Kalle Aho (ORCID: https://orcid.org/0009-0009-6172-4348)
- Sami Heikkinen (ORCID: https://orcid.org/0000-0001-6976-2028)
- Ave Kivisild
- Johanna Krüger (ORCID: https://orcid.org/0000-0003-4346-1133)
- Laura Tervonen
- Kasper Katisko (ORCID: https://orcid.org/0000-0001-7463-1989)
- Antti Kilpeläinen (ORCID: https://orcid.org/0000-0003-4299-0578)
- Mikko Aaltonen (ORCID: https://orcid.org/0000-0002-3686-2986)
- Reetta Kälviäinen
- Iina Rinnankoski
- Adolfina Lehtonen
Institutions
- University of Eastern Finland (FI)
- Oulu University Hospital (FI)
- Kuopio University Hospital (FI)
- University of Oulu (FI)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1001/jamaneurol.2025.1358
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41