Adenovirus vectors can infect mouse megakaryocytes – implications for vaccine-induced thrombosis/thrombocytopenia
We found that adenoviral infection was higher in higher-ploidy CD41<sup>+</sup>CD42<sup>+</sup> and CXCR4<sup>hi</sup> MKs, implicating these receptors in the MK response to adenoviral infection.
Authors
- Simon Collett (ORCID: https://orcid.org/0000-0001-8559-9603)
- Julio Carrera Montoya (ORCID: https://orcid.org/0000-0002-2503-5643)
- Chantal Attard (ORCID: https://orcid.org/0000-0002-4428-1663)
- Ashley P. Ng (ORCID: https://orcid.org/0000-0001-9690-0879)
- Joseph Torresi (ORCID: https://orcid.org/0000-0002-8212-0887)
- Linda Earnest (ORCID: https://orcid.org/0000-0003-0586-621X)
- Melissa A. Edeling (ORCID: https://orcid.org/0000-0002-8672-8339)
- Alison Farley (ORCID: https://orcid.org/0000-0002-9609-8983)
- Paul Monagle (ORCID: https://orcid.org/0000-0002-3970-8984)
- Ashley Huey Yiing Yap
- Ladina Di Rago
Institutions
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Walter and Eliza Hall Institute of Medical Research (AU)
- Peter MacCallum Cancer Centre (AU)
- Peter Doherty Institute (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102909
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health and Medical Research Council