Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes
This multi-omics study in aging nonhuman primates provides novel insights into the metabolic dysregulations associated with TM and obesity in cardiac tissues. The observed metabolic changes highlight potential therapeutic targets for prevention or mitigating the cardiac complications of TM.
Authors
- Wenhui Yang (ORCID: https://orcid.org/0000-0001-5740-1364)
- Haizhen Wang (ORCID: https://orcid.org/0000-0001-8135-4297)
- Yao Ma (ORCID: https://orcid.org/0000-0003-0815-7910)
- Fei Sun (ORCID: https://orcid.org/0000-0002-2969-2501)
- Haiyan Wu (ORCID: https://orcid.org/0000-0001-5322-3425)
- Chongye Fang
- Hao Hu (ORCID: https://orcid.org/0000-0003-3622-9897)
- Yaowen Liu (ORCID: https://orcid.org/0000-0003-1408-7509)
- Shaoxia Pu
- Jingning Yu (ORCID: https://orcid.org/0000-0002-4047-568X)
Institutions
- Kunming University of Science and Technology (CN)
- Yunnan Agricultural University (CN)
- Fuwai Yunnan Cardiovascular Hospital (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Aging
- Published
- 2025-06-02
- DOI
- https://doi.org/10.18632/aging.206261
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China
- Yunnan University