Association of hematopoietic loss of Y chromosome with valvular heart disease incidence and sex susceptibility
Mosaic LOY is independently associated with increased risk of incident VHD and contributes to the observed sex differences in VHD susceptibility.
Authors
- Tianqi Ma (ORCID: https://orcid.org/0000-0002-2919-4764)
- Yuanfeng Huang (ORCID: https://orcid.org/0009-0005-0423-8491)
- Yongping Bai (ORCID: https://orcid.org/0000-0002-6355-5842)
- Jinchen Li (ORCID: https://orcid.org/0000-0001-5522-806X)
- Xunjie Cheng (ORCID: https://orcid.org/0000-0001-8766-0594)
- Yu Tan
- Guogang Zhang (ORCID: https://orcid.org/0000-0002-8678-2167)
- Chenxuan Zhao (ORCID: https://orcid.org/0000-0002-3966-4897)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1016/j.jare.2025.06.001
- Citations
- 1
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Hunan Province
- Science and Technology Program of Hunan Province
- National Key Research and Development Program of China