Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors
The LC-MS raw datasets that support the findings of this study have been deposited in the online repository: MassIVE ( https://massive.ucsd.edu/ProteoSAFe/static/massive.jsp ) with accession no. MSV000090212.
Authors
- Shane S. Kelly (ORCID: https://orcid.org/0000-0002-6252-5895)
- Paul Piehowski (ORCID: https://orcid.org/0000-0001-5108-2227)
- Ronald Moore (ORCID: https://orcid.org/0000-0003-2806-2855)
- Rohit Kulkarni (ORCID: https://orcid.org/0000-0001-5029-6119)
- Elizabeth A. Butterworth (ORCID: https://orcid.org/0000-0001-7365-9832)
- Vladislav Petyuk (ORCID: https://orcid.org/0000-0003-4076-151X)
- Mark A. Atkinson (ORCID: https://orcid.org/0000-0001-8489-4782)
- Weijun Qian (ORCID: https://orcid.org/0000-0002-5393-2827)
- Adam Swensen (ORCID: https://orcid.org/0000-0001-8135-1766)
- Clayton E. Mathews (ORCID: https://orcid.org/0000-0002-8817-6355)
- Lith Nasif (ORCID: https://orcid.org/0000-0001-5515-6115)
- Martha Campbell‐Thompson (ORCID: https://orcid.org/0000-0001-6878-1235)
- Jing Chen (ORCID: https://orcid.org/0000-0002-2681-0349)
- X’avia Y. Chan
Institutions
- Joslin Diabetes Center (US)
- Beth Israel Deaconess Medical Center (US)
- Pacific Northwest National Laboratory (US)
- University of Florida (US)
- Harvard Stem Cell Institute (US)
- Florida College (US)
Publication Details
- Journal
- Diabetologia
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1007/s00125-025-06417-3
- Citations
- 3
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Diabetes and Digestive and Kidney Diseases