Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult

Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk sac tumor. Despite guideline-directed systemic chemotherapy, the course was complicated by tumor-related bleeding and venous thromboembolism, resulting in death from massive pulmonary embolism. This case highlights the aggressiveness of adult yolk sac tumors and need for early intervention.

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Publication Details

Journal
Urology Case Reports
Published
2025-06-02
DOI
https://doi.org/10.1016/j.eucr.2025.103091
Primary Topic
Testicular diseases and treatments
Type
article
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article

Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult

Gilberto Ruiz-Deyá, Rosa María Galán Sánchez, Merary Z Nazario-Perez, A P Quiles-Méndez et al.
Urology Case Reports
Testicular diseases and treatments
article

Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult

Gilberto Ruiz-Deyá, Rosa María Galán Sánchez, Merary Z Nazario-Perez, A P Quiles-Méndez, I Pastrana-Echevarría
article en

Abstract

Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk sac tumor. Despite guideline-directed systemic chemotherapy, the course was complicated by tumor-related bleeding and venous thromboembolism, resulting in death from massive pulmonary embolism. This case highlights the aggressiveness of adult yolk sac tumors and need for early intervention.

Urology Case ReportsVol. 61
Pontifical Catholic University of Puerto Rico (PR), Ponce Health Sciences University (PR), Central University of the Caribbean (PR), Ross University School of Veterinary Medicine (KN), St. Luke's Hospital (US)
Zero hunger
Openalex Percentile: Top 78%
Testicular diseases and treatments
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Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult — Gilberto Ruiz-Deyá, Rosa María Galán Sánchez, et al. · Urology Case Reports (2025) | TGRS Research Map | TGRS