Critically ill patients with necrotizing soft tissue infections in the Caribbean area: unsupervised analysis of a retrospective cohort (2014–2023) with identification of factors associated with mortality
Unsupervised analysis of critically ill patients with NSTIs in tropical settings revealed three distinct patient clusters that exhibited unique phenotypic characteristics and clinical outcomes. Upon hospital admission, patients with NSTIs should be carefully screened for sepsis-associated encephalopathy, subcutaneous emphysema, and thrombopenia. The present exploratory results must be confirmed in larger multicentric cohorts.
Authors
- B. Tressières (ORCID: https://orcid.org/0000-0002-9585-4281)
- Sébastien Breurec (ORCID: https://orcid.org/0000-0003-4188-0377)
- Marc Valette
- Laurent Camous (ORCID: https://orcid.org/0000-0002-0265-429X)
- Frédéric Martino (ORCID: https://orcid.org/0000-0002-1389-2306)
- Alexandre Demoule (ORCID: https://orcid.org/0000-0002-0432-7217)
- Jean‐David Pommier (ORCID: https://orcid.org/0000-0001-9154-7607)
- Nejla Aissa
- Pascale Piednoir (ORCID: https://orcid.org/0000-0003-4809-2912)
- Pascal Blanchet
- Frédéric Desmoulins
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre de Neurophysique Physiologie et Pathologie (FR)
- Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale (FR)
- Établissement Français du Sang (FR)
- Institut Pasteur de la Guadeloupe (GP)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01488-2
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00