A Retrospective Study of Fetal Congenital Anomalies In Tertiary Care Hospital

Background:Congenital anomalies are a significant cause of fetal morbidity and mortality. Fetal autopsy remains the gold standard for confirming congenital malformations and assessing recurrence risk. Methods:A retrospective review was conducted on fetal autopsy at a tertiary care hospital over a defined period. Cases with confirmed congenital anomalies were analysed for prevalence, type of anomaly and associated clinical details. Anomalies were categorized system-wise to identify the most commonly affected systems. Results:Out of 264 fetal autopsies examined, congenital anomalies were observed in 100 cases (37%). Central nervous system malformations were the most prevalent, followed by musculoskeletal, cardiovascular, and renal anomalies. Multiple system involvement was also noted. Conclusion:Fetal autopsy pathology is crucial for accurate diagnosis, guiding genetic counseling and preventing recurrence through targeted interventions and improved antenatal care.

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Publication Details

Journal
Journal of Neonatal Surgery
Published
2025-06-02
DOI
https://doi.org/10.63682/jns.v14i30s.6914
Primary Topic
Congenital Anomalies and Fetal Surgery
Type
article
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article

A Retrospective Study of Fetal Congenital Anomalies In Tertiary Care Hospital

Ashwini Ratnakar, Manasi Gosavi, Deshpande Ketaki Makarand, Aneta Mynarova
Journal of Neonatal Surgery
Congenital Anomalies and Fetal Surgery
article

A Retrospective Study of Fetal Congenital Anomalies In Tertiary Care Hospital

Ashwini Ratnakar, Manasi Gosavi, Deshpande Ketaki Makarand, Aneta Mynarova
article en

Abstract

Background:Congenital anomalies are a significant cause of fetal morbidity and mortality. Fetal autopsy remains the gold standard for confirming congenital malformations and assessing recurrence risk. Methods:A retrospective review was conducted on fetal autopsy at a tertiary care hospital over a defined period. Cases with confirmed congenital anomalies were analysed for prevalence, type of anomaly and associated clinical details. Anomalies were categorized system-wise to identify the most commonly affected systems. Results:Out of 264 fetal autopsies examined, congenital anomalies were observed in 100 cases (37%). Central nervous system malformations were the most prevalent, followed by musculoskeletal, cardiovascular, and renal anomalies. Multiple system involvement was also noted. Conclusion:Fetal autopsy pathology is crucial for accurate diagnosis, guiding genetic counseling and preventing recurrence through targeted interventions and improved antenatal care.

Journal of Neonatal SurgeryVol. 14(30S)
Openalex Percentile: Top 78%
Congenital Anomalies and Fetal Surgery
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A Retrospective Study of Fetal Congenital Anomalies In Tertiary Care Hospital — Ashwini Ratnakar, Manasi Gosavi, et al. · Journal of Neonatal Surgery (2025) | TGRS Research Map | TGRS