Impact of Recovery from Febrile Neutropenia on Intra-Individual Variability in Vancomycin Pharmacokinetics in Pediatric Patients
Maximum daily body temperature was identified as a factor influencing intra-individual variability in CLvcm in pediatric FN patients, particularly during the recovery process from FN to a non-FN state. The finding suggests that dose adjustment based on maximum daily body temperature may allow safe and effective VCM therapy in FN patients.
Authors
- Ryosuke Tatsuta (ORCID: https://orcid.org/0000-0003-4949-362X)
- Yukie Takumi
- Motoshi Iwao (ORCID: https://orcid.org/0000-0002-6551-6345)
- Ryota Tanaka (ORCID: https://orcid.org/0000-0002-8452-7971)
- Hiroki Itoh
Institutions
- Oita University Hospital (JP)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-06-02
- DOI
- https://doi.org/10.3390/antibiotics14060570
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Research Foundation for Clinical Pharmacology