Percutaneous Closure of Coexisting Patent Foramen Ovale and Atrial Septal Defect in a Rare Case of Platypnea-Orthodeoxia Syndrome

Summary An 82-year-old woman presented with exertional dyspnea and positional hypoxemia. Transesophageal echocardiography revealed the presence of both a patent foramen ovale (PFO) and an atrial septal defect (ASD). Percutaneous closure of both defects was performed using a dual-device approach, which led to immediate and sustained improvement in the patient's symptoms.