Correlation analysis of mitochondrial DNA maintenance-related genes with HCC prognosis, tumor mutation burden and tumor microenvironment features
mtDNA MRGs play important roles in HCC TMB, prognosis, clinicopathological features and the immune microenvironment. The mtDNA score can be used to evaluate HCC prognosis, TMB and the immune microenvironment, thereby providing guidance for treatment decision making and prognosis prediction in HCC patients.
Authors
- Zhongji Meng (ORCID: https://orcid.org/0000-0003-0401-535X)
- Rong Fan (ORCID: https://orcid.org/0000-0001-5616-5515)
- Bin Cheng (ORCID: https://orcid.org/0000-0003-1568-8760)
- Shaobo Zeng
- Ling Guo (ORCID: https://orcid.org/0000-0002-3591-2144)
- Xunliang Xu
Institutions
- Hubei University of Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1371/journal.pone.0325033
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61