Intelligent and precise auxiliary diagnosis of breast tumors using deep learning and radiomics
We developed an intelligent diagnostic model combining deep learning and radiomics to enhance breast tumor diagnosis. The model integrates MobileNet with ResNeXt-inspired depthwise separable and grouped convolutions, improving feature processing and efficiency while reducing parameters. Using AI-Dhabyani and TCIA breast ultrasound datasets, we validated the model internally and externally, comparing it to VGG16, ResNet, AlexNet, and MobileNet. Results: The internal validation set achieved an accuracy of 83.84% with an AUC of 0.92, outperforming other models. The external validation set showed an accuracy of 69.44% with an AUC of 0.75, demonstrating high robustness and generalizability. Conclusions: We developed an intelligent diagnostic model using deep learning and radiomics to improve breast tumor diagnosis. The model combines MobileNet with ResNeXt-inspired depthwise separable and grouped convolutions, enhancing feature processing and efficiency while reducing parameters. It was validated internally and externally using the AI-Dhabyani and TCIA breast ultrasound datasets and compared with VGG16, ResNet, AlexNet, and MobileNet.
Authors
- Chui Kong (ORCID: https://orcid.org/0000-0002-3855-5867)
- Yi Yu
- Ting Wang (ORCID: https://orcid.org/0000-0003-2257-0699)
- Xiaomin Yang
- Yi‐Gang Li
- Boyang Zang
Institutions
- Fudan University (CN)
- XinHua Hospital (CN)
- Shanghai Chest Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1371/journal.pone.0320732
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00