The Evolving Therapeutic Landscape of Hereditary Angioedema in Canada: Clinical Advances and Unmet Needs

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent, potentially life‑threatening episodes of swelling due to bradykinin overproduction. Advances in the understanding of molecular pathophysiology, coupled with the development of innovative therapies, are transforming the management of hereditary angioedema. This underscores the need for strategic planning to incorporate emerging treatment modalities into the Canadian therapeutic framework for HAE.

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Publication Details

Journal
Canadian allergy & immunology today.
Published
2025-06-02
DOI
https://doi.org/10.58931/cait.2025.5180
Primary Topic
Coagulation, Bradykinin, Polyphosphates, and Angioedema
Type
article
Field-Weighted Citation Impact
0.00
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article

The Evolving Therapeutic Landscape of Hereditary Angioedema in Canada: Clinical Advances and Unmet Needs

Dawn M. Goodyear
Canadian allergy & immunology today.
Coagulation, Bradykinin, Polyphosphates, and Angioedema
article

The Evolving Therapeutic Landscape of Hereditary Angioedema in Canada: Clinical Advances and Unmet Needs

Dawn M. Goodyear
article en

Abstract

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent, potentially life‑threatening episodes of swelling due to bradykinin overproduction. Advances in the understanding of molecular pathophysiology, coupled with the development of innovative therapies, are transforming the management of hereditary angioedema. This underscores the need for strategic planning to incorporate emerging treatment modalities into the Canadian therapeutic framework for HAE.

Canadian allergy & immunology today.
Malawi Blood Transfusion Service (MW)
Openalex Percentile: Top 82%
Coagulation, Bradykinin, Polyphosphates, and Angioedema
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