Electrocardiographic alterations in patients treated for acute Lassa Fever: Description of results from a phase II clinical trial in Nigeria

ECG alterations observed in both treatment arms are compatible with direct cardiac effects of the LASV. The combination of new onset of chest pain combined with the evolution of ECG findings over time are suggestive for the occurrence of perimyocarditis in a subset of patients.

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Publication Details

Journal
Journal of Infection and Public Health
Published
2025-06-02
DOI
https://doi.org/10.1016/j.jiph.2025.102858
Citations
3
Primary Topic
Disaster Response and Management
Type
article
Field-Weighted Citation Impact
7.55
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article

Electrocardiographic alterations in patients treated for acute Lassa Fever: Description of results from a phase II clinical trial in Nigeria

Sylvanus Okogbenin, Michael Ramharter, ThankGod Akhigbe, Alexandre Duvignaud et al.
3 citations
Journal of Infection and Public Health
Disaster Response and Management
7.55
article

Electrocardiographic alterations in patients treated for acute Lassa Fever: Description of results from a phase II clinical trial in Nigeria

Sylvanus Okogbenin, Michael Ramharter, ThankGod Akhigbe, Alexandre Duvignaud, Augusto Meneguim, Cyril Erameh, Sampson Omagbemi Owhin, Oladele Oluwafemi Ayodeji, Georg Goliasch, Nelson Adedosu, Mirjam Groger, Stephan Günther, Till F. Omansen, Chukwuyem Abejegah, Meike Pahlmann, Peter Akhideno, Osahogie Isaac Edeawe, Kevin Okwaraeke, Enomen Ekata, Marie Jaspard, Liasu Adeagbo Ahmed
article en
3 citations

Abstract

ECG alterations observed in both treatment arms are compatible with direct cardiac effects of the LASV. The combination of new onset of chest pain combined with the evolution of ECG findings over time are suggestive for the occurrence of perimyocarditis in a subset of patients.

Journal of Infection and Public HealthVol. 18(9)
Université de Bordeaux (FR), Inserm (FR), Universität Hamburg (DE), Centre Hospitalier Universitaire de Bordeaux (FR), Bordeaux Population Health (FR), University Medical Center Hamburg-Eppendorf (DE), Hôpital Pellegrin (FR), German Center for Infection Research (DE), Federal Medical Centre (NG), Federal Medical Centre (NG), Irrua Specialist Teaching Hospital (NG), Institut de Recherche pour le Développement (FR), Medical University of Vienna (AT), Bernhard Nocht Institute for Tropical Medicine (DE)
Good health and well-being
Openalex Percentile: Top 3%
Disaster Response and Management
7.55
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