The Vasopressin Biomarker Copeptin Is Linked to Systemic Inflammation and Refines Prognostication in Decompensated Cirrhosis
In patients with dACLD, copeptin is independently linked to systemic inflammation. The MELD-copeptin score identifies patients with dACLD at risk for impaired clinical outcomes.
Authors
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Richard Moreau (ORCID: https://orcid.org/0000-0003-0862-403X)
- Joan Clària (ORCID: https://orcid.org/0000-0003-4333-7749)
- David Bauer (ORCID: https://orcid.org/0000-0002-9363-8518)
- Michael Schwarz (ORCID: https://orcid.org/0000-0002-2587-1385)
- Annarein Kerbert (ORCID: https://orcid.org/0000-0001-9845-2176)
- Nina Dominik (ORCID: https://orcid.org/0009-0009-4615-915X)
- Benedikt Simbrunner (ORCID: https://orcid.org/0000-0001-8181-9146)
- Jonel Trebicka (ORCID: https://orcid.org/0000-0002-7028-3881)
- Lukas Hartl (ORCID: https://orcid.org/0000-0003-3398-6120)
- Minneke J. Coenraad (ORCID: https://orcid.org/0000-0002-3434-4421)
- Thierry Thévenot (ORCID: https://orcid.org/0000-0003-3974-2784)
- Michael Trauner
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- Benedikt Silvester Hofer (ORCID: https://orcid.org/0000-0003-3403-3372)
- Rodrig Marculescu (ORCID: https://orcid.org/0000-0003-1772-6695)
- Mathias Jachs (ORCID: https://orcid.org/0000-0003-2871-4147)
- Lorenz Balcar (ORCID: https://orcid.org/0000-0002-6708-3061)
- Georg Kramer (ORCID: https://orcid.org/0009-0008-1736-3699)
- Marlene Hintersteininger
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Leiden University Medical Center (NL)
- Centre Hospitalier Universitaire de Besançon (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- European Foundation for the Study of Chronic Liver Failure (ES)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Clinical Gastroenterology and Hepatology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1016/j.cgh.2025.04.030
- Citations
- 4
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 5.29
Funders
- Gilead Sciences
- Siemens
- Medizinische Universität Wien