Diagnostic utility of the revised Lake Louise criteria in myocarditis associated with active autoimmune rheumatic disease
In patients with suspected myocarditis due to autoimmune rheumatic disease, who are receiving immunosuppressive therapy, the LLC have a high specificity, but a lower sensitivity than in patients with viral myocarditis. Additional tests should therefore be used to improve disease detection in this population. Where the pre-test probability is high, in patients with suspected myocarditis due to autoimmune rheumatic disease who are undergoing immunosuppression, there may need to be greater reliance on one T1-based criterion rather than both LLC, with the recognition that there is an appreciable rate of raised T1 in controls without myocarditis.
Authors
- David D’Cruz (ORCID: https://orcid.org/0000-0002-6983-8421)
- Tevfik F. Ismail (ORCID: https://orcid.org/0000-0002-1691-7599)
- Amedeo Chiribiri (ORCID: https://orcid.org/0000-0003-3394-4289)
- Michael Marber (ORCID: https://orcid.org/0000-0002-3463-7128)
- Michelle Fernando (ORCID: https://orcid.org/0000-0002-1545-0309)
- Alina Hua (ORCID: https://orcid.org/0000-0002-2648-7326)
- Giovanni Sanna (ORCID: https://orcid.org/0009-0000-7804-6189)
- Ronak Rajani (ORCID: https://orcid.org/0000-0002-8816-6296)
- Blanca Domènech-Ximenos (ORCID: https://orcid.org/0000-0001-5109-4463)
- Begoña Lopez
Institutions
- St Thomas' Hospital (GB)
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Hospital Clínic de Barcelona (ES)
- King's College School (GB)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jocmr.2025.101916
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00