Diastereoselective reaction to construct polycyclic spiroindolines from 3-(2-isocyanoethyl)indoles and ynones
A cascade reaction of tryptamine-derived isocyanide and ynone under transition metal-free conditions has been developed. This domino transformation allows for the synthesis of polycyclic spiroindolines with excellent diastereoselectivity.
Authors
- Demin Liang
- Jie Shen (ORCID: https://orcid.org/0000-0003-1768-8748)
- Xiaodong Yan (ORCID: https://orcid.org/0000-0001-9972-6888)
- Jiale Wang (ORCID: https://orcid.org/0000-0003-3830-1995)
- Jian Li (ORCID: https://orcid.org/0000-0002-3136-5112)
- Shanya Lu
- Wu Da
Institutions
- Shanghai University (CN)
- China Tobacco (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj01268f
- Citations
- 1
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94