Longitudinal change and causal relationship between gut microbiota and gestational diabetes mellitus
Significant alterations in the relative abundance of Ruminococcaceae UCG-002 and Odoribacter were observed throughout the three trimesters of pregnancy in women with GDM. Elevated levels of Prevotella 9 in early trimester were causally associated with an increased risk of GDM, while Methanobrevibacter exhibited protective effects.
Authors
- Hongzhuan Tan (ORCID: https://orcid.org/0000-0002-4292-5947)
- Juan Song (ORCID: https://orcid.org/0000-0001-5872-6806)
- Shujuan Ma (ORCID: https://orcid.org/0000-0002-7858-067X)
- Yixiong Tan (ORCID: https://orcid.org/0000-0002-9493-9849)
- Xinpeng Liu (ORCID: https://orcid.org/0000-0002-0184-821X)
- Xinrui Wu (ORCID: https://orcid.org/0000-0002-6077-4855)
Institutions
- Central South University (CN)
- Jishou University (CN)
- Reproductive & Genetic Hospital CITIC-Xiangya (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1186/s13098-025-01737-1
- Citations
- 5
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 10.29
Funders
- Education Department of Hunan Province
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province
- Division of Graduate Education