Prediction of healthy mitral valve hemodynamics in children and adults: validation of fluid-structure interaction simulations against echocardiography and magnetic resonance imaging
A computational framework for clinically feasible patient-specific prediction of mitral valve hemodynamics was developed and validated in vivo in the largest cohort presented to date. Computational time was acceptable for clinical planning. This is a step towards personalized surgical planning of valve repair and an increased understanding of the hemodynamics and mitral valve function after intervention.
Authors
- Lea Christierson (ORCID: https://orcid.org/0009-0003-6188-4575)
- Petter Frieberg (ORCID: https://orcid.org/0000-0002-1966-6692)
- Nina Hakacova (ORCID: https://orcid.org/0000-0002-6757-6237)
- Johan Revstedt (ORCID: https://orcid.org/0000-0003-3215-3098)
- Erik Hedström (ORCID: https://orcid.org/0000-0003-0041-9357)
- Petru Liuba
- Hanna Isaksson (ORCID: https://orcid.org/0000-0002-9690-8907)
Institutions
- Lund University (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Computers in Biology and Medicine
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1016/j.compbiomed.2025.110455
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00