Solitary fibrous tumor in the lower limb: A rare case report emphasizing the importance of long-term surveillance

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm of fibroblastic differentiation, characterized by unpredictable biological behavior. Although initially described in the pleura, it may occur in extrapleural sites, including soft tissues of the limbs, although this is uncommon. The definitive diagnosis relies on histopathological analysis combined with immunohistochemical markers such as CD34 and STAT6, the latter being highly sensitive and specific for SFT. While SFT often exhibits an indolent course, approximately 10% to 30% of cases may develop local recurrences or metastases, reinforcing the importance of prognostic risk stratification and long-term follow-up after surgical resection. • Case report of a rare solitary fibrous tumor (SFT) in the lower limb. • Diagnosis was difficult and required immunohistochemistry (CD34 and STAT6) . • Tumor came back 17 months after surgery , showing the need for long-term follow-up. • Limited access to tests in low-income areas can delay diagnosis and treatment. • The study highlights the need for better hospital resources and trained professionals .

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Publication Details

Journal
Medical Reports
Published
2025-06-02
DOI
https://doi.org/10.1016/j.hmedic.2025.100270
Primary Topic
Soft tissue tumor case studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Solitary fibrous tumor in the lower limb: A rare case report emphasizing the importance of long-term surveillance

Jessica Vanina Ortiz, Luis Enrique Bermejo Galan, Ana Cássia Silva Oliveira, Felipe A. Cerni et al.
Medical Reports
Soft tissue tumor case studies
article

Solitary fibrous tumor in the lower limb: A rare case report emphasizing the importance of long-term surveillance

Jessica Vanina Ortiz, Luis Enrique Bermejo Galan, Ana Cássia Silva Oliveira, Felipe A. Cerni, Manuela B. Pucca, Glyciane Vieira da Silva, Roberto Carlos Cruz Carbonell, Pablo André Brito de Souza, Geovanna M. Malachias-Pires, Bruna Kempfer Bossoli
article en

Abstract

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm of fibroblastic differentiation, characterized by unpredictable biological behavior. Although initially described in the pleura, it may occur in extrapleural sites, including soft tissues of the limbs, although this is uncommon. The definitive diagnosis relies on histopathological analysis combined with immunohistochemical markers such as CD34 and STAT6, the latter being highly sensitive and specific for SFT. While SFT often exhibits an indolent course, approximately 10% to 30% of cases may develop local recurrences or metastases, reinforcing the importance of prognostic risk stratification and long-term follow-up after surgical resection. • Case report of a rare solitary fibrous tumor (SFT) in the lower limb. • Diagnosis was difficult and required immunohistochemistry (CD34 and STAT6) . • Tumor came back 17 months after surgery , showing the need for long-term follow-up. • Limited access to tests in low-income areas can delay diagnosis and treatment. • The study highlights the need for better hospital resources and trained professionals .

Medical ReportsVol. 13
Universidade Federal de Roraima (BR), Centro Universitário de Araraquara (BR), Universidade Estadual Paulista (Unesp) (BR)
Fundação de Amparo à Pesquisa do Estado de São Paulo
Openalex Percentile: Top 81%
Soft tissue tumor case studies
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Solitary fibrous tumor in the lower limb: A rare case report emphasizing the importance of long-term surveillance — Jessica Vanina Ortiz, Luis Enrique Bermejo Galan, et al. · Medical Reports (2025) | TGRS Research Map | TGRS