Impact of Puberty on Immune Responses to <i>Mycobacterium tuberculosis</i> in South African Adolescents
While in healthy individuals there was a strong association between Tanner stage and endocrine markers, this relationship was absent in adolescents with TB. TB disease appears to disrupt the normal physiologic process of puberty. This could have a substantial impact on growth and development for adolescents developing TB during this critical time.
Authors
- Candice Snyders (ORCID: https://orcid.org/0000-0002-8571-6029)
- Elizna Maasdorp (ORCID: https://orcid.org/0000-0002-3402-169X)
- Léanie Kleynhans (ORCID: https://orcid.org/0000-0003-1635-253X)
- James A. Seddon (ORCID: https://orcid.org/0000-0002-2296-2302)
Institutions
- South African Medical Research Council (ZA)
- Western Cape Department of Health (ZA)
- Desmond Tutu HIV Foundation (ZA)
- Stellenbosch University (ZA)
- Mater Research (AU)
- Imperial College London (GB)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1093/infdis/jiaf293
- Citations
- 1
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- South African Medical Research Council
- Department for International Development
- Universiteit Stellenbosch
- Medical Research Council
- Faculty of Medicine and Health, University of Sydney