Reversal of phenotypic resistance in multi-drug resistant carbapenemase-producing <i>K. pneumoniae</i> clinical isolates due to <i>in vitro</i> synergistic interactions between bacteriophages and antibiotics at clinically achievable concentrations
The phage-antibiotic combinations were synergistic against more than half of the isolates for all antibiotics except ciprofloxacin reversing resistance in most strains particularly with amikacin.
Authors
- Paschalis Paranos (ORCID: https://orcid.org/0000-0003-1934-8691)
- Joseph Meletiadis (ORCID: https://orcid.org/0000-0002-8869-1509)
- Sophia Vourli (ORCID: https://orcid.org/0000-0003-0878-5124)
- Maria Siopi (ORCID: https://orcid.org/0000-0002-5924-1007)
- Eleni Papanikolaou (ORCID: https://orcid.org/0000-0002-9008-5823)
- Spyros Pournaras (ORCID: https://orcid.org/0000-0002-6298-9577)
- Panagoula Kolia
Institutions
- National and Kapodistrian University of Athens (GR)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1093/jac/dkaf163
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Hellenic Foundation for Research and Innovation