Association of longitudinal triglyceride levels with cardiovascular events in multivessel coronary artery disease
Triglycerides are intricately associated with metabolic disorders that contribute to atherosclerotic events; however, the relationship between individual triglyceride trajectories and adverse cardiovascular outcomes in individuals with stable coronary artery disease (CAD) remains unclear. Using a cohort of 1020 patients with chronic CAD under long-term follow-up, we observed that greater triglyceride variability was associated with an increased cardiovascular risk, and this risk remained significant in individuals who previously had controlled triglyceride levels compared with those with persistently altered levels since baseline.
Authors
- Paulo Cury Rezende (ORCID: https://orcid.org/0000-0001-8625-1537)
- Rosa Maria Rahmi Garcia (ORCID: https://orcid.org/0000-0003-1547-6282)
- Maria Stanislavovna Tairova
- Whady Hueb (ORCID: https://orcid.org/0000-0002-3166-6054)
- Paulo Rogério Soares
- Arthur Cicupira Rodrigues de Assis (ORCID: https://orcid.org/0009-0004-9244-3593)
- José Antônio Franchini Ramires (ORCID: https://orcid.org/0000-0002-6296-605X)
- Marcela Francisca da Silva
- Roberto Kalil Filho (ORCID: https://orcid.org/0000-0002-1033-3672)
- Luciano da Silva Selistre (ORCID: https://orcid.org/0000-0002-0152-0636)
- Thiago Luis Scudeler (ORCID: https://orcid.org/0000-0001-5685-3633)
- Mauricio Rigodanzo Mocha (ORCID: https://orcid.org/0000-0001-8994-2771)
- Matheus de Oliveira Laterza Ribeiro (ORCID: https://orcid.org/0000-0002-8221-0778)
- Vitor Coutinho Andrade
- Ary Serpa Neto
Institutions
- The University of Melbourne (AU)
- Hospital Israelita Albert Einstein (BR)
- Austin Hospital (AU)
- Universidade de Caxias do Sul (BR)
- Victoria University of Wellington (NZ)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Instituto do Coração (PT)
- Monash University (AU)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1093/eurjpc/zwaf192
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01