SNORA13 antisense oligonucleotides enhances the therapeutical effects of 5-fluorouracil in colon adenocarcinoma
Our study revealed <i>SNORA13</i> is highly expressed in CRC and demonstrated knockdown of <i>SNORA13</i>, especially combined with 5-FU administration, may represent a promising therapeutic approach for CRC treatment.
Authors
- Huihui An
- Qing Lyu (ORCID: https://orcid.org/0000-0002-1325-6828)
- Yaou Zhang (ORCID: https://orcid.org/0000-0002-2501-8093)
- Zhe Zhang (ORCID: https://orcid.org/0000-0003-2365-2362)
- Yanzhi Wang (ORCID: https://orcid.org/0000-0003-4767-7230)
Institutions
- Chongqing University (CN)
- China-Japan Friendship Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.3389/fphar.2025.1564682
- Citations
- 1
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China