The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy
HOXA11-AS is a critical regulator of normal endometrial development. HOXA11-AS is elevated in endometriosis contributes to its pathophysiology. This long non-coding RNA was decreased in women undergoing endometriosis treatment with progestins. HOXA11-AS regulated several key drivers of disease and repression during treatment likely has a central role in preventing growth and invasion of endometriosis.
Authors
- Rula Atwani (ORCID: https://orcid.org/0009-0009-2851-7574)
- Irene Moridi
- Ramanaiah Mamillapalli (ORCID: https://orcid.org/0000-0002-4022-8910)
- Hugh S. Taylor (ORCID: https://orcid.org/0000-0003-1720-8310)
- Nimisha Gawde
- Monica Fay
Institutions
- Yale University (US)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1186/s12958-025-01420-0
- Citations
- 2
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.40
Funders
- Endometriosis Foundation of America
- National Institutes of Health