The role of heparin in preventing early thrombosis of arteriovenous fistula for hemodialysis: An observational Study

Arteriovenous fistula (AVF) is preferred for hemodialysis. However, early thrombosis often leads to failure. Hence, this observational study of 200 patients compared AVF outcomes with and without intraoperative heparin use. Thrombosis within 30 days was significantly lower in the heparin group (11% vs. 25%, p = 0.01). Smaller vein diameter was an independent risk factor, while heparin improved maturation and short-term patency. Despite minor bleeding, heparin prophylaxis was safe and may reduce early AVF failure.

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Published
2025-05-31
DOI
https://doi.org/10.6026/973206300211149
Primary Topic
Central Venous Catheters and Hemodialysis
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article
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The role of heparin in preventing early thrombosis of arteriovenous fistula for hemodialysis: An observational Study

Ruchi Singh, Tushar Kumar, Alok Kumar Bharti, Madhav Kumar et al.
Bioinformation
Central Venous Catheters and Hemodialysis
article

The role of heparin in preventing early thrombosis of arteriovenous fistula for hemodialysis: An observational Study

Ruchi Singh, Tushar Kumar, Alok Kumar Bharti, Madhav Kumar, Aandrei Jivendra Jha
article en

Abstract

Arteriovenous fistula (AVF) is preferred for hemodialysis. However, early thrombosis often leads to failure. Hence, this observational study of 200 patients compared AVF outcomes with and without intraoperative heparin use. Thrombosis within 30 days was significantly lower in the heparin group (11% vs. 25%, p = 0.01). Smaller vein diameter was an independent risk factor, while heparin improved maturation and short-term patency. Despite minor bleeding, heparin prophylaxis was safe and may reduce early AVF failure.

BioinformationVol. 21(05)
Patna Medical College and Hospital (IN), Indira Gandhi Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 79%
Central Venous Catheters and Hemodialysis
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