Development, Formulation, And Evaluation Of The Antibacterial Properties Of A Herbal Toothpaste Prepared From The Seeds Of Chebulic Myrobalan

Medicinal plants are an integral part of human society in fighting against diseases.Chebulic myrobalan (Terminalia chebula), often referred to as the "King of Medicine" in Tibet and holds a prominent place in Ayurvedic medicine due to its excellent healing properties.The entire plant possesses significant medicinal value and has been traditionally used for the treatment of various diseases.The aim of the present study was to formulate antibacterial herbal toothpaste using Chebulic myrobalan.Fresh fruits were sourced from the local market in Haveri and authenticated by a taxonomist.The powdered fruit was extracted using 70% ethanol through maceration for 48 hours.Three toothpaste formulations (F1, F2, and F3) were prepared using varying concentrations of the extract.These formulations underwent evaluation for physical characteristics, pH, foamability, moisture content, and antimicrobial activity (zone of inhibition).Among them, the F3 formulation demonstrated superior physicochemical properties and exhibited the highest antibacterial activity, particularly against Escherichia coli.