AN INSIGHT INTO MEDICINAL PROPERTIES OF QUINOXALINE SCAFFOLD, WITH A FOCUS ON THEIR ANTICANCER POTENTIAL AS INTERCALATING AGENTS

The antitumor properties of synthetic heterocyclic compounds are among the most important properties that can be made use in medicinal chemistry. More specifically, their significant cytotoxic effects against many types of human tumor cells, as well as their roles as various topoisomerase inhibitors. In recent years, quinoxaline derivatives have frequently attracted the interest of medicinal chemistry researchers due to their promising anticancer properties. The present study is a review of the latest advances in quinoxaline derivative-related research, with a focus on their anticancer activities as DNA intercalator.