Hemodynamics in a curved artery with mild stenosis: A two-layered model

Arterial stenosis is the leading cause of cardiovascular disease and significantly contributes to premature death worldwide, which indicates the need for deeper research into its dynamics. This abnormal narrowing of the arterial lumen affects hemodynamics, and more effect is seen if the curvature is also present at the same location. Because the materials, flow patterns, and thickness are different in the core and peripheral layer of the artery, a two-layered model can address the situation correctly. A new model is developed in this work after incorporating a quadratic curvature term in conservative form in the Navier–Stokes equation. The equation is then solved to get analytical solutions for the flow parameters in a curved stenotic region of an artery and the results are analyzed. The velocity profile, volumetric flow rate, pressure gradient and shear stress decrease due to curvature and effect of curvature is less for more viscous fluid. The result obtained is more appropriate and realistic than in the one-layer model. This model helps to understand the blood flow system in cardiovascular arteries with mild stenosis before reaching the pathological conditions, and many lives can be saved.

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Publication Details

Journal
International Journal of Thermofluids
Published
2025-05-01
DOI
https://doi.org/10.1016/j.ijft.2025.101253
Citations
2
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
4.01
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article

Hemodynamics in a curved artery with mild stenosis: A two-layered model

Pushpa Nidhi Gautam, Jeevan Kafle, Chudamani Pokharel, Tuk Bahadur Rana
2 citations
International Journal of Thermofluids
Coronary Interventions and Diagnostics
4.01
article

Hemodynamics in a curved artery with mild stenosis: A two-layered model

Pushpa Nidhi Gautam, Jeevan Kafle, Chudamani Pokharel, Tuk Bahadur Rana
article en
2 citations

Abstract

Arterial stenosis is the leading cause of cardiovascular disease and significantly contributes to premature death worldwide, which indicates the need for deeper research into its dynamics. This abnormal narrowing of the arterial lumen affects hemodynamics, and more effect is seen if the curvature is also present at the same location. Because the materials, flow patterns, and thickness are different in the core and peripheral layer of the artery, a two-layered model can address the situation correctly. A new model is developed in this work after incorporating a quadratic curvature term in conservative form in the Navier–Stokes equation. The equation is then solved to get analytical solutions for the flow parameters in a curved stenotic region of an artery and the results are analyzed. The velocity profile, volumetric flow rate, pressure gradient and shear stress decrease due to curvature and effect of curvature is less for more viscous fluid. The result obtained is more appropriate and realistic than in the one-layer model. This model helps to understand the blood flow system in cardiovascular arteries with mild stenosis before reaching the pathological conditions, and many lives can be saved.

International Journal of ThermofluidsVol. 27
Tribhuvan University (NP), Nepal Development Research Institute (NP)
Openalex Percentile: Top 7%
Coronary Interventions and Diagnostics
4.01
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Hemodynamics in a curved artery with mild stenosis: A two-layered model — Pushpa Nidhi Gautam, Jeevan Kafle, et al. · International Journal of Thermofluids (2025) | TGRS Research Map | TGRS