TRANSIENT RENAL TUBULAR ACIDOSIS IN PREGNANCY

INTRODUCTION/BACKGROUNDHypokalemia during pregnancy is a rare yet significant condition that can predispose to rhabdomyolysis, as demonstrated in this case report of a 27-year-old female. CASEWe report a case of hypokalemia-induced rhabdomyolysis due to RTA (renal tubular acidosis) which occurred in 2 subsequent pregnancies. During her second pregnancy at 28 weeks gestation, the patient developed severe hypokalemia-induced rhabdomyolysis secondary to transient renal tubular acidosis (RTA), a condition also observed during her first pregnancy. Clinical findings included profound hypokalemia (2.1 mmol/L), metabolic acidosis, renal potassium wasting, and markedly elevated creatinine kinase levels. Immediate management with potassium supplementation and hydration led to symptom resolution, and the patient had an uneventful postpartum recovery. CONCLUSIONThis case highlights the rarity and complexity of transient yet recurrent RTA in pregnancy in association with rhabdomyolysis, emphasizing the importance of early diagnosis and multidisciplinary management to prevent feto-maternal complications. Follow-up and preemptive care in subsequent pregnancies are recommended.

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Publication Details

Journal
Journal of the ASEAN Federation of Endocrine Societies
Published
2025-05-30
DOI
https://doi.org/10.15605/jafes.040.s1.009
Primary Topic
Electrolyte and hormonal disorders
Type
article
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article

TRANSIENT RENAL TUBULAR ACIDOSIS IN PREGNANCY

Suprhamanyam Evali, Thurgaashini Sivanesan, Pritina Raventhran
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Journal of the ASEAN Federation of Endocrine Societies
Electrolyte and hormonal disorders
article

TRANSIENT RENAL TUBULAR ACIDOSIS IN PREGNANCY

Suprhamanyam Evali, Thurgaashini Sivanesan, Pritina Raventhran
article en

Abstract

INTRODUCTION/BACKGROUNDHypokalemia during pregnancy is a rare yet significant condition that can predispose to rhabdomyolysis, as demonstrated in this case report of a 27-year-old female. CASEWe report a case of hypokalemia-induced rhabdomyolysis due to RTA (renal tubular acidosis) which occurred in 2 subsequent pregnancies. During her second pregnancy at 28 weeks gestation, the patient developed severe hypokalemia-induced rhabdomyolysis secondary to transient renal tubular acidosis (RTA), a condition also observed during her first pregnancy. Clinical findings included profound hypokalemia (2.1 mmol/L), metabolic acidosis, renal potassium wasting, and markedly elevated creatinine kinase levels. Immediate management with potassium supplementation and hydration led to symptom resolution, and the patient had an uneventful postpartum recovery. CONCLUSIONThis case highlights the rarity and complexity of transient yet recurrent RTA in pregnancy in association with rhabdomyolysis, emphasizing the importance of early diagnosis and multidisciplinary management to prevent feto-maternal complications. Follow-up and preemptive care in subsequent pregnancies are recommended.

Journal of the ASEAN Federation of Endocrine SocietiesVol. 40(S1)
Openalex Percentile: Top 79%
Electrolyte and hormonal disorders
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TRANSIENT RENAL TUBULAR ACIDOSIS IN PREGNANCY — Suprhamanyam Evali, Thurgaashini Sivanesan, et al. · Journal of the ASEAN Federation of Endocrine Societies (2025) | TGRS Research Map | TGRS