Bicarbonate from arterial blood gas analysis as predictor of sleep-related hypoventilation: a diagnostic accuracy study
The sensitivity of elevated bicarbonate from awake arterial blood gas analysis using common cut-off values such as 27 mmol/L is only moderate, and bicarbonate as an integral part of the assessment of sleep hypoventilation (likelihood ratio) must be interpreted in the context of other assessments. A normal bicarbonate does not rule out sleep hypoventilation.
Authors
- Malcolm Kohler (ORCID: https://orcid.org/0000-0003-1800-8003)
- Matteo Bradicich (ORCID: https://orcid.org/0000-0001-6380-7395)
- Silvia Ulrich (ORCID: https://orcid.org/0000-0002-5250-5022)
- Mona Lichtblau (ORCID: https://orcid.org/0000-0003-4485-1758)
- Michelle Mollet
- Esther Irene Schwarz (ORCID: https://orcid.org/0000-0001-8840-981X)
- Laura C. Mayer (ORCID: https://orcid.org/0009-0004-4949-8548)
- Joël Julien Herzig
- Sanja Pocrncic
- Louise Benning (ORCID: https://orcid.org/0000-0002-8366-2100)
Institutions
- ZHAW Zurich University of Applied Sciences (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-002591
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00