Serum neurofilament light is superior to glial fibrillary acidic protein to distinguish sporadic frontotemporal dementia from late-onset primary psychiatric disorders: a retrospective DIPPA-FTD study
Our study found that serum GFAP does not provide additional value as a discriminative marker compared with serum NfL alone when differentiating sporadic bvFTD from late-onset PPD.
Authors
- Ishana Rue (ORCID: https://orcid.org/0000-0002-8954-1078)
- Ramón Landín-Romero (ORCID: https://orcid.org/0000-0003-0485-8090)
- Andrea Arighi (ORCID: https://orcid.org/0000-0003-2865-3970)
- Zac Chatterton (ORCID: https://orcid.org/0000-0002-6683-1400)
- Glenda Margaret Halliday (ORCID: https://orcid.org/0000-0003-0422-8398)
- Olivier Piguet (ORCID: https://orcid.org/0000-0002-6696-1440)
- Sven J. van der Lee (ORCID: https://orcid.org/0000-0003-1606-8643)
- Lina Riedl (ORCID: https://orcid.org/0000-0002-0658-5332)
- Inge M.W. Verberk (ORCID: https://orcid.org/0000-0003-0341-7445)
- Charlotte Elisabeth Teunissen (ORCID: https://orcid.org/0000-0002-4061-0837)
- Chiara Fenoglio (ORCID: https://orcid.org/0000-0001-6332-4721)
- Janine Diehl‐Schmid (ORCID: https://orcid.org/0000-0002-7745-1382)
- Daniela Galimberti (ORCID: https://orcid.org/0000-0002-9284-5953)
- Sterre C.M. de Boer (ORCID: https://orcid.org/0000-0002-9595-7221)
- Yolande A.L. Pijnenburg (ORCID: https://orcid.org/0000-0003-2464-1905)
- Sophie Matis (ORCID: https://orcid.org/0009-0005-1458-2181)
- Simon Ducharme (ORCID: https://orcid.org/0000-0002-7309-1113)
- Lisa Wissink
Institutions
- Montreal Neurological Institute and Hospital (CA)
- The University of Sydney (AU)
- University of Milan (IT)
- Douglas Mental Health University Institute (CA)
- TUM Klinikum (DE)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- UNSW Sydney (AU)
- Ospedale Maggiore (IT)
- Cooperative Trials Group for Neuro-Oncology (AU)
- Amsterdam Neuroscience (NL)
- Universität Bayern (DE)
- Inn-Salzach-Klinikum (DE)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- BMJ Neurology Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/bmjno-2024-001007
- Citations
- 4
- Primary Topic
- Prion Diseases and Protein Misfolding
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- McGill University
- EU Joint Programme – Neurodegenerative Disease Research
- Technische Universität München
- Medical Research Council
- National Health and Medical Research Council