Differences in Neutrophil Counts Between African and Non-African Countries in 2 International Clinical Trials

Differences in baseline median ANC can result in misclassification of adverse events or inappropriate clinical management. Development and use of population-specific normal values of ANC could improve guidance for research and clinical management.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-05-29
DOI
https://doi.org/10.1093/infdis/jiaf291
Primary Topic
Neutropenia and Cancer Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Differences in Neutrophil Counts Between African and Non-African Countries in 2 International Clinical Trials

Chi Chiu Leung, Ziyaad Waja, Grace Muzanyi, Stefan Goldberg et al.
The Journal of Infectious Diseases
Neutropenia and Cancer Infections
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Differences in Neutrophil Counts Between African and Non-African Countries in 2 International Clinical Trials

Chi Chiu Leung, Ziyaad Waja, Grace Muzanyi, Stefan Goldberg, John L. Johnson, Ruth N. Moro, Neil Alexander Martinson, Kwok Chiu Chang
article en

Abstract

Differences in baseline median ANC can result in misclassification of adverse events or inappropriate clinical management. Development and use of population-specific normal values of ANC could improve guidance for research and clinical management.

The Journal of Infectious DiseasesVol. 232(5)
Centers for Disease Control and Prevention (US), Department of Health (CN), Johns Hopkins University (US), University of the Witwatersrand (ZA), University Hospitals of Cleveland (US), Johns Hopkins Medicine (US), Hong Kong Tuberculosis, Chest and Heart Diseases Association (CN), Infectious Diseases Research Collaboration (UG), Perinatal HIV Research Unit (ZA), University School (US), Case Western Reserve University (US)
Sanofi, Centers for Disease Control and Prevention
Good health and well-being
Openalex Percentile: Top 81%
Neutropenia and Cancer Infections
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