Study of Properties of Polymer Film Materials Based on Polycaprolactone–Chitosan–Ceftriaxone Blends

Properties of compositions based on polycaprolactone, chitosan, and antibiotic ceftriaxone, which are designed for the protection and treatment of long nonhealing wounds, have been studied. It is shown that despite the fact that the film materials are obtained by melt processing at a temperature of 80°C, they possess microbiological activity against Staphylococcus aureus and Pseudomonas aeruginosa. It is demonstrated that varying the content of ceftriaxone and chitosan in the composition makes it possible to control the moisture absorption capacity of the material and the release of drug substance from the film coating, as well as the values of elastic modulus, tensile strength, and elongation at break.