The pH-controlled release properties of chitosan–gold nanoparticles encapsulated nobiletin to induce apoptosis through PI3K/AKT/mTOR signalling pathway on gastric cancer cell lines
Ch-AuNPs-NB inhibited the PI3K/AKT/mTOR pathway, induced apoptosis, and arrested the cell cycle in AGS cells, highlighting its potential as a targeted GC therapy.
Authors
- Wenhai Fan
- Zhenjiang Wu
- Xu Xiulian
- Yuanxiao Liang (ORCID: https://orcid.org/0009-0007-8488-2096)
- Ping Xie (ORCID: https://orcid.org/0000-0003-4257-8970)
- Huiguo Qing (ORCID: https://orcid.org/0009-0000-7044-1563)
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Journal of Microencapsulation
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1080/02652048.2025.2507638
- Citations
- 2
- Primary Topic
- Bioactive Compounds in Plants
- Type
- article
- Field-Weighted Citation Impact
- 3.50