Metabolic alterations in the umbilical cord blood of pregnant women with uncontrolled type 2 diabetes mellitus: a matched-case comparative study in metabolomics
The metabolic profile of umbilical cord blood among pregnant women with uncontrolled T2DM was different from that of the healthy pregnant women. The metabolic profile of umbilical cord blood from the uncontrolled T2DM women was characterized by the enrichment of the pathways of biosynthesis of amino acids and butanoate metabolism and the metabolites of alisol A and L-leucine.
Authors
- Muqiu Zhang
- Huixia Yang (ORCID: https://orcid.org/0000-0001-8954-2102)
- Jie Yan (ORCID: https://orcid.org/0000-0003-4895-3567)
- Shuting Wan (ORCID: https://orcid.org/0000-0003-1687-9702)
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1186/s13098-025-01742-4
- Citations
- 1
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- Peking University First Hospital
- National Natural Science Foundation of China
- Peking University
- National Key Research and Development Program of China