Recombinant Protein UBC13 Improves Tissue Injury of MRL/Lpr Mice by Alleviating Th1/Th2 Immune Imbalance
UBC13 restores the homeostasis and function of Th1/Th2 and Treg cell through suppression of STAT3 and the NF-κB signaling pathway activation, thereby mitigating SLE-induced organ damage.
Authors
- Yulong Yang (ORCID: https://orcid.org/0000-0002-5104-309X)
- Qian Li (ORCID: https://orcid.org/0009-0009-9079-4986)
- Junbing Jiang (ORCID: https://orcid.org/0000-0002-7191-6062)
- Li‐Kang Zhang (ORCID: https://orcid.org/0000-0003-3757-8116)
- Mengchen Qi
- Ling Guo (ORCID: https://orcid.org/0009-0002-0968-232X)
- Binhai Ren (ORCID: https://orcid.org/0000-0003-2400-4682)
- Jiali Tao
- Bing Sun (ORCID: https://orcid.org/0000-0002-4407-3135)
Institutions
- Shanxi Agricultural University (CN)
- Jinzhong University (CN)
- Institute of Engineering (NP)
- Shanxi Science and Technology Department (CN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1080/08820139.2025.2509086
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00