Intravascular Myopericytoma of the Foot: A Diagnostic Challenge

Myopericytoma is a rare pericytic tumor, typically occurring in the skin and subcutaneous tissue, though cases in internal organs and bones have been reported. Clinically, it presents as a painless, slow-growing mass, making differential diagnosis challenging. Imaging alone is often insufficient due to overlapping characteristics with angioleiomyoma, glomus tumors, and solitary fibrous tumors (SFT). Histopathological examination is essential for accurate diagnosis. Here, we report a rare case of intravascular myopericytoma of the foot. MRI findings suggested multiple differential diagnoses, but histopathology confirmed the tumor. Immunohistochemistry supported the diagnosis. Marginal excision was performed, and no recurrence was observed after three years. Given the overlapping imaging characteristics of pericytic tumors, histopathological analysis is crucial for distinguishing myopericytoma from similar entities and ensuring proper treatment and management. This case highlights the importance of comprehensive evaluation when diagnosing pericytic tumors in distal extremities.