Chemoresistance in Patients with Resected Locally Advanced Lymph Node-Positive Colon Cancer and Poorly Controlled T2DM: What Relationship?

Colon cancer (CC) ranks among the most common cancers globally, with its occurrence steadily rising in numerous countries. However, advancements in diagnostic methods, monitoring techniques, and surgical procedures have led to significant progress. Adjuvant chemotherapy is the standard treatment for patients with resected, locally advanced, lymph node-positive (stage III) colon cancer.