Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study
This study highlights the potential of SGJPF as a therapeutic strategy for TNBC through its modulation of the SRC/ERK/STAT3 signaling axis, offering a robust foundation for further investigation into its clinical application.
Authors
- L. T. Li (ORCID: https://orcid.org/0009-0003-9753-6169)
- Shulong Shi
- Tinghao Yan (ORCID: https://orcid.org/0009-0004-6970-7140)
- Dengtian Zhang
- Xinchen Tian (ORCID: https://orcid.org/0000-0002-7517-3462)
- Jian‐Lin Wu (ORCID: https://orcid.org/0000-0002-3875-185X)
- Shulong Jiang (ORCID: https://orcid.org/0000-0001-8034-6762)
- Yiming Zhang (ORCID: https://orcid.org/0000-0002-8933-1871)
- Fen Liu (ORCID: https://orcid.org/0000-0001-9214-0016)
- Jiaqi Zhang (ORCID: https://orcid.org/0000-0002-7449-4176)
- Ni Zhang (ORCID: https://orcid.org/0009-0005-0130-2240)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Shandong University (CN)
- People's Liberation Army 401 Hospital (CN)
- Jining First People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/dddt.s518123
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00