Efficacy and safety of Lignosus rhinocerus (Cooke) Ryvarden TM02® supplementation for immune-challenged patients with localised breast cancer in remission: a randomised controlled trial
Our study found that TM02<sup>®</sup>, a natural supplement containing standardized compounds from Lignosus rhinocerus, is well tolerated in patients with localized breast cancer post-adjuvant chemotherapy. TM02<sup>®</sup> supplementation showed a positive trend towards improved physical functioning and reduced fatigue scores.
Authors
- Muhammad Fazril Mohamad Razif (ORCID: https://orcid.org/0000-0002-3951-8136)
- Mohammed H. Saad (ORCID: https://orcid.org/0000-0003-1511-6690)
- Zamri Chik (ORCID: https://orcid.org/0000-0003-1770-8382)
- J. Eng (ORCID: https://orcid.org/0009-0005-5469-6220)
- Shin Yee Fung (ORCID: https://orcid.org/0000-0002-9288-7328)
- Mahmoud Danaee (ORCID: https://orcid.org/0000-0002-5014-5684)
- Po Lin Ooi (ORCID: https://orcid.org/0000-0003-2089-6118)
- Nur Aishah Mohd Taib (ORCID: https://orcid.org/0000-0001-8419-0478)
- Chee Loong Lam (ORCID: https://orcid.org/0000-0001-7643-3230)
- Mariam Zafirah
Institutions
- University Malaya Medical Centre (MY)
- University of Malaya (MY)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1186/s12906-025-04919-6
- Citations
- 1
- Primary Topic
- Phytochemicals and Antioxidant Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.77