Effect of Intraoperative Intravenous Infusion of Esketamine Combined with Dexmedetomidine on Postoperative Sleep Disturbance in Patients Undergoing Radical Mastectomy
Intraoperative infusion of esketamine combined with dexmedetomidine had no significant effect on POSD, but dexmedetomidine reduced REM sleep, and esketamine reduced the nocturnal awakening time.
Authors
- Yutian Pu
- Gao‐Chao Lv (ORCID: https://orcid.org/0000-0001-5440-0411)
- Ziwei Hu (ORCID: https://orcid.org/0000-0002-6650-555X)
- Jingru Wu (ORCID: https://orcid.org/0000-0001-9333-9609)
- Xiuxia Chen (ORCID: https://orcid.org/0000-0003-3318-6721)
- Can Fang (ORCID: https://orcid.org/0000-0003-3119-9748)
- Xiaoxuan Fan (ORCID: https://orcid.org/0000-0002-4091-0717)
- Xingyu Geng (ORCID: https://orcid.org/0009-0002-3665-1801)
- Wanting Li (ORCID: https://orcid.org/0009-0003-7186-4594)
- Su Liu (ORCID: https://orcid.org/0000-0002-8402-3765)
- Maosan Wang (ORCID: https://orcid.org/0009-0004-6784-2357)
- Heling Zhang
- Xinyue Zhang (ORCID: https://orcid.org/0009-0005-5743-8649)
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/dddt.s510222
- Citations
- 2
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 2.79