Impact of hypoalbuminemia on patients receiving ertapenem combination therapy for methicillin-susceptible <i>Staphylococcus aureus</i> bacteraemia
Among patients with persistent MSSA bacteraemia who were treated with ertapenem combination therapy, patients with hypoalbuminemia had a significantly longer time to negative blood cultures. Pharmacokinetic studies are warranted to confirm if these findings are due to drug exposures or the underlying condition of patients with hypoalbuminemia.
Authors
- Brandon Smith
- Lingyi Peng
- Sunish Shah (ORCID: https://orcid.org/0000-0002-8873-1451)
- G.K. Balasubramani (ORCID: https://orcid.org/0000-0001-7221-1825)
- Ryan K. Shields (ORCID: https://orcid.org/0000-0001-9794-5665)
- Lloyd Clarke
Institutions
- University of Pittsburgh (US)
- Department of Health (TW)
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1093/jac/dkaf134
- Citations
- 4
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 5.42