A Rare Case of Non-Ossifying Fibroma in a 32-Year-Old Man: Case Report and Review of Literature

Background: Non-ossifying fibroma is a benign fibrohistiocytic bone tumor and occurs mostly in the metaphysis of long bones. Non-ossifying fibroma of the rib is extremely rare. Case presentation: Herein, a case of a 32-year-old man who was referred for a prolonged cough after an accident was presented. CT scan revealed a well-defined expansile lesion in the right 11th rib. Due to the uncertainty of the diagnosis, a core needle biopsy was taken from the lesion. The biopsy showed proliferated bland fibroblasts admixed with multinucleated giant cells and hemosiderin deposition. Based on the imaging findings and H&E studies, non-ossifying fibroma of the rib was confirmed. Conclusion: Although the most common sites of non-ossifying fibroma are metaphysis of long bones, they can occur in any bone. The diagnosis of non-ossifying fibroma is based on radiological findings, and the correct diagnosis in imaging studies reduces invasive procedures