A TFPN-mediated acyl fluoride platform: efficient synthesis of esters, thioesters, and macrolactones from carboxylic acids with diverse nucleophiles

A TFPN-mediated esterification strategy enables the rapid synthesis of esters, thioesters, and macrolactones via in situ acyl fluorides. This process has a broad substrate scope and excellent functional group tolerance, as well as stereoretention.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00651a
Citations
4
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
Field-Weighted Citation Impact
3.74
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article

A TFPN-mediated acyl fluoride platform: efficient synthesis of esters, thioesters, and macrolactones from carboxylic acids with diverse nucleophiles

Qiuyi Zheng, Peng Shen, Silin Xu, Jiahui Zhang et al.
4 citations
Organic Chemistry Frontiers
Sulfur-Based Synthesis Techniques
3.74
article

A TFPN-mediated acyl fluoride platform: efficient synthesis of esters, thioesters, and macrolactones from carboxylic acids with diverse nucleophiles

Qiuyi Zheng, Peng Shen, Silin Xu, Jiahui Zhang, Yao Zhang, Dou Zhang, Jinhua Yang, Chunyu Han
article en
4 citations

Abstract

A TFPN-mediated esterification strategy enables the rapid synthesis of esters, thioesters, and macrolactones via in situ acyl fluorides. This process has a broad substrate scope and excellent functional group tolerance, as well as stereoretention.

Organic Chemistry FrontiersVol. 12(20)
Hubei Normal University (CN), Xuchang University (CN)
Openalex Percentile: Top 7%
Sulfur-Based Synthesis Techniques
3.74
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