Formulation of Antibacterial Herbal Cream from Mimusops elengi Flower Extract

Introduction: Mimusops elengi (Spanish cherry) is a well-known medicinal plant and used traditionally from ancient year in the different medicinal systems such as Ayurveda and Siddha etc.The flowers of Mimusops elengi have antibacterial and wound healing properties.Objective: The aim was to formulate the antibacterial herbal cream by using Mimusops elengi flower extract and evaluate the herbal cream.Material and method: Mimusops elengi flower powder was extracted using 70% methanol via maceration for 48h.The cream was formulated through Trituration method, using Beeswax as an emulsifier, Borax as a buffering agent, Liquid paraffin as an emollient, and Sodium benzoate as a preservative.Water was used as the solvent, Rose oil as a fragrance and Peppermint oil as a soothing agent.The Methnolic extract of flower was incorporated at various concentrations to evaluate its antibacterial effectiveness by Zone of Inhibition studies.Results: The Mimusops elengi flower extract containing phytoconstituents flavonoids, terpenoids and phenols were present.Among the three formulations tested, Formulation 3 emerged as the most effective in terms of antibacterial activity against the pathogen, with a zone of inhibition is 10.1 mm.The pH was 6.69 and viscosity of the formulation F3 was 3927cps.The Spreadability of F3 is 7.38 gcm/sec along with no phase separation in the formulation F3.The formulation F3 was found to be in stable by physical evaluation and stability studies.Conclusion: The results showed that the formulated cream can be used for bacterial infections.This formulation required further researcher and development of commercial standard.