Tumor-secreted galectin-3 suppresses antitumor response by inducing IL-10<sup>+</sup> B cells
Gal-3 is a crucial regulator of immune evasion in BRCA. Targeting Gal-3 may improve the efficacy of BRCA therapies.
Authors
- Zhenghao Wu (ORCID: https://orcid.org/0000-0001-8468-1234)
- Wenhao Niu (ORCID: https://orcid.org/0000-0003-2797-9418)
- Qianheng Wang (ORCID: https://orcid.org/0009-0000-5619-8384)
- Tao Huang (ORCID: https://orcid.org/0000-0003-2130-8621)
- Yibing Lv (ORCID: https://orcid.org/0000-0002-8768-4489)
- Yunxiao Xiao
- Meng Li (ORCID: https://orcid.org/0000-0001-6631-0819)
- Jing Cao (ORCID: https://orcid.org/0009-0000-2161-8385)
- Yirui Zhang (ORCID: https://orcid.org/0000-0002-0601-9496)
- Junyi Xiao (ORCID: https://orcid.org/0000-0003-2000-5581)
- Peng Zheng (ORCID: https://orcid.org/0009-0005-8072-6331)
Institutions
- Union Hospital (HK)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1136/jitc-2024-011445
- Citations
- 3
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 2.39