Indeterminate malignant potential glomus tumor of the esophagus: A case report

Esophageal GT-UMP diagnosis requires multimodal correlation: characteristic immunohistochemical profile (smooth muscle markers positivity) combined with WHO size/location criteria. The absence of recurrence in this large (5 cm) GT-UMP case challenges current size-based risk stratification, suggesting biological heterogeneity within this classification. Molecular profiling and extended (>5 years) follow-up are imperative to establish reliable prognostic markers for visceral glomus tumors.