Antiplatelet Use Prior to Anticoagulant Initiation in Patients With Atrial Fibrillation-Related Ischemic Stroke: An ELAN Trial Analysis
Following an AF-associated ischemic stroke, we found a lower risk of recurrence and no signs of net harm with antiplatelet use before DOAC initiation, despite an increased risk of bleeding.
Authors
- Markus Kneihsl (ORCID: https://orcid.org/0000-0002-6334-9432)
- Ana Paiva Nunes (ORCID: https://orcid.org/0000-0002-5573-1551)
- Urs Fischer (ORCID: https://orcid.org/0000-0003-0521-4051)
- Martina Goeldlin (ORCID: https://orcid.org/0000-0001-5800-116X)
- Manju Krishnan (ORCID: https://orcid.org/0009-0000-8581-5679)
- Alexandros A. Polymeris (ORCID: https://orcid.org/0000-0002-9475-2208)
- Liqun Zhang (ORCID: https://orcid.org/0000-0001-6983-7915)
- Sven Poli (ORCID: https://orcid.org/0000-0002-0286-8781)
- Gek Shim
- Vedamurthy Adhiyaman (ORCID: https://orcid.org/0000-0002-7670-5715)
- Daniel Strbian (ORCID: https://orcid.org/0000-0001-9095-2344)
- Marjaana Tiainen (ORCID: https://orcid.org/0000-0001-5107-1990)
- Masatoshi Koga (ORCID: https://orcid.org/0000-0002-6758-4026)
- Daria Giudici
- Espen Saxhaug Kristoffersen (ORCID: https://orcid.org/0000-0002-8999-5424)
- Christoph Gumbinger (ORCID: https://orcid.org/0000-0002-6137-1169)
- Nicoletta Caracciolo (ORCID: https://orcid.org/0000-0002-8260-1680)
- Jesse Dawson (ORCID: https://orcid.org/0000-0001-7532-2475)
- Peter Vanacker (ORCID: https://orcid.org/0000-0003-2169-5123)
- Silja Räty (ORCID: https://orcid.org/0000-0002-6921-0597)
- Timo Kahles (ORCID: https://orcid.org/0000-0002-1569-6376)
- Angelika Alonso (ORCID: https://orcid.org/0000-0003-2487-7205)
- Mattia Branca
- Thomas Horvath (ORCID: https://orcid.org/0000-0002-6537-6821)
- Philippe Desfontaines
Institutions
- University of Bern (CH)
- Betsi Cadwaladr University Health Board (GB)
- Swansea Bay University Health Board (GB)
- Beth Israel Deaconess Medical Center (US)
- University of Helsinki (FI)
- Harvard University (US)
- University of Oslo (NO)
- University of Basel (CH)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- University of Perugia (IT)
- Akershus University Hospital (NO)
- AZ Groeninge (BE)
- University Hospital of North Durham (GB)
- Helsinki University Hospital (FI)
- University Hospital of Bern (CH)
- University Hospital Heidelberg (DE)
- University Hospital of Basel (CH)
- Centre Hospitalier Chrétien (BE)
- Unidade Local de Saúde de São José (PT)
- National Cerebral and Cardiovascular Center (JP)
- St George's Hospital (GB)
- Hertie Institute for Clinical Brain Research (DE)
- University Medical Centre Mannheim (DE)
- Queen Elizabeth University Hospital (GB)
- Kantonsspital Aarau (CH)
- University of Tübingen (DE)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of Stroke
- Published
- 2025-05-30
- DOI
- https://doi.org/10.5853/jos.2024.04322
- Citations
- 3
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- National Science Foundation
- Pfizer
- AstraZeneca
- Biogen
- Alexion Pharmaceuticals
- CSL Behring
- Stryker
- Schweizerischen Neurologischen Gesellschaft
- National Cerebral and Cardiovascular Center
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Daiichi-Sankyo
- Schweizerische Herzstiftung
- Angelini Pharma